Older adults admitted to hospitals with higher prescribing rates of first-generation antihistamines are more likely to experience delirium.
A study published in the Journal of the American Geriatrics Society found an association between the prescribing of first-generation antihistamines and delirium in older general medicine inpatients.
No direct quote available in the text.
Author's summary: Delirium risk increases with first-generation antihistamines in seniors.