Key Nervous System Components Influence Gastrointestinal Tumour Growth
Recent research has found that common nervous system components are present in the gastrointestinal tract, where they influence tumour growth, revealing new opportunities for cancer treatment.
The gut contains its own nervous system, often referred to as the "second brain". Neuropeptides, signalling factors produced and released by nerves, play a key role in this system. They relay messages throughout the nervous system by connecting to receptors on the outside of cells, influencing various processes.
- CGRP, a common neuropeptide, and its receptor RAMP1 have been found to influence tumour growth in colorectal and stomach cancers.
Researchers at the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe School of Cancer Medicine made this discovery, creating promising new avenues for treatment with existing approved therapies.
Author's summary: Research reveals nervous system components influence gastrointestinal tumour growth.
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