NFL Picks and Predictions for Week 6
The NFL season continues with a highly-anticipated slate of games in Week 6, prompting consideration of 3 plus-money bets before kickoff.
By Spenser Davis, published on Oct 12, 2025.
Week 6 Predictions
Last week's NFL bold predictions yielded a 2-1 result and a total of +1.17 units. Since Week 3, the picks in this story have accumulated 2.16 units.
This Week's Bets
- Fading the Colts offense, despite their current average of 3.39 points per drive, which would be the highest this century if maintained throughout the season.
Indianapolis is currently averaging 3.39 points per drive.
Author's summary: NFL Week 6 predictions include 3 plus-money bets.
More News
- Mamdani, Cuomo neck and neck in NYC mayoral race if Curtis Sliwa drops out: poll
- Watch 'Conclave' thriller at De Valence!
- Who Killed the Montreal Expos? Review: Vive les Expos! - POV Magazine
- Son of ex-England football captain killed in tractor crash near Cirencester
- A scandal waiting to happen
- Disney+ and Hulu Cancellation Rates Doubled Amid Jimmy Kimmel Suspension Saga
- Reform in turmoil: Party forced to suspend 4 more Kent councillors after bitter infighting
- Best Apple TV Original Shows of 2025
- Supreme Court Declines to Hear Corner-Crossing Case
- A Portrait of Chuck Brown Made With Images of DC Culture Anchors This New Exhibit - Washingtonian